Fenacetină
Fenacetină CAS:62-44-2
Fenacetină Chemical Properties
MF: C10H13NO2
MW: 179,22
Punct de topire: 133-136 ° C (lit.)
Punct de fierbere: 132 ° C / 4mmHg
Densitate: 1,1248 (estimare brută)
Fenacetină Specification:
Analiza% â ¥ 99,0
clorură organică% â ‰ ¤0.02
p-Fenetidină ... roșu deschis € 4 #
Compus ușor de carbon ... ¤4 # ã € 6 #
Pierdere la uscare% ‰ ¤0,5
Punct de topire: 134-137oC
Reziduul de aprindere% ‰ ¤0.1
Fenacetină Introduction:
Fenacetină is a non-opioid analgesic without anti-inflammatory properties, inhibits COX-3 activity.Target: COXFenacetină is a pain-relieving and fever-reducing drug,
Fenacetină was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy. the clinical and laboratory data were compatible with“phenacetin nephritis”as described in Europe and Australia and recently in the United States and Canada.
This report evaluates the findings in the 23 cases and cautions against the use of phenacetin, particularly in patients with impaired renal function [1]. Fenacetină has been linked to renal papillary necrosis in human beings [2, 3].
Fenacetină Application:
Analgezic antipiretic, utilizat pentru tratamentul febrei, cefaleei, nevralgiei etc.
